Publisher's Note: Modulation of dorsal root ganglion development by ErbB signaling and the scaffold protein Sorbs3 by Malmquist et al. Development doi:10.1242/dev.084640.

Publisher's Note: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium by El-Hashash et al. Development doi:10.1242/dev.058479.

Publisher's Note: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium by El-Hashash et al. Development This Publisher's Note relates to the article 'Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium' by El-Hashash et al. (doi:10.1242/dev.058479). We have recently bee...

Neuregulin-mediated ErbB3 signaling is required for formation of zebrafish dorsal root ganglion neurons.

Dorsal root ganglia (DRGs) arise from trunk neural crest cells that emerge from the dorsal neuroepithelium and coalesce into segmental streams that migrate ventrally along the developing somites. Proper formation of DRGs involves not only normal trunk neural crest migration, but also the ability of DRG progenitors to pause at a particular target location where they can receive DRG-promoting sig...

Publisher's Note: Rho differentially regulates the Hippo pathway by modulating the interaction between Amot and Nf2 in the blastocyst. Development doi: 10.1242/dev.157917.

Defective adgra2 (gpr124) splicing and function in zebrafish ouchless mutants.

A hitherto unidentified N-ethyl-N-nitrosourea (ENU)-induced mutation affects dorsal root ganglia (DRG) formation in ouchless mutant zebrafish larvae. In contrast to previous findings assigning the ouchless phenotypes to downregulated sorbs3 transcript levels, this work re-attributes the phenotypes to an essential splice site mutation affecting adgra2 (gpr124) splicing and function. Accordingly,...

Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation.

Vertebrate pigment cells are derived from neural crest cells and are a useful system for studying neural crest-derived traits during post-embryonic development. In zebrafish, neural crest-derived melanophores differentiate during embryogenesis to produce stripes in the early larva. Dramatic changes to the pigment pattern occur subsequently during the larva-to-adult transformation, or metamorpho...